CB 399: Viruses as Tools for Genetic Analysis Spring 2016

Viruses as Tools for Genetic Analysis

Course Director: Dr. Constance Cepko

Curriculum Fellows:   Emily Gleason, emily_gleason@hms.harvard.edu and Christopher Burtner, christopher_burtner@hms.harvard.edu

For decades, the unique properties of viruses have been harnessed by biologists as tools for genetic analysis. Currently viruses are employed in a wide range of techniques from basic research to therapeutic approaches. This course will start with an introduction to viral biology and how aspects of this biology can be harnessed for various research applications. We will then discuss two types of commonly used viruses in more detail; Adeno-Associated Virus (AAV) and retroviruses.

Lecturers:

  • Constance Cepko, Department of Genetics, Harvard Medical School
  • Luk Vandenberghe, Schepens Eye Research Institute, Massachusetts Eye and Ear Infirmary, Harvard Medical School

Schedule: 

First Session (open to the Harvard community): Monday, April 4, 2016 1 – 4:30 PM
Location: The Cannon Room, Building C

Second Session (limited to registered students): Monday, April 11, 2016 1 – 3:30 PM
Location: TMEC 448

Assignment:
Registered students should prepare a one-page proposal to be discussed during the second session of the course. Begin your proposals with a question you plan to answer using viral tools and some brief background information about this area of research. Next, based on the information and discussion in the first session, state which viral vector you would use to answer your question and justify your answer. In addition to the lecture slides, we have provided a suggested reference list (attached the the bottom of the page, you must be logged in to view them).

Proposals must be e-mailed to Chris and Emily (christopher_burtner@hms.harvard.edu and emily_gleason@hms.harvard.edu) no later than 5pm on Friday, April 8th and be submitted in either .doc, .docx, or .pdf formats with your last name included in the file name. Emily and Chris will compile the proposals and email them to the class and to the teaching staff. You are expected to read your classmates’ proposals and come to class prepared to discuss them. 


DROP DEADLINE: Monday, March 28, 2016

 

AUDITORS (Post-Docs, Faculty, or Staff) DO NOT NEED TO SIGN UP TO ATTEND THE 1st SESSION.  PLEASE DO NOT ENROLL