CB 399: Public Health 101 - Metabolomics: an exciting and novel approach for the exploration of human nutrition, health and disease Summer 2015

Public Health 101 - Metabolomics: an exciting and novel approach for the exploration of human nutrition, health and disease 

Course Director: Dr. Eric Rubin
Course Instructors: Kerry Ivey and Rachel Kelly

Curriculum Fellow:  Zofia Gajdos (Zofia_Gajdos@hms.harvard.edu)

Metabolomics, an interdisciplinary “omics” science, that combines bioinformatics, epidemiology, analytical biochemistry and biology, may represent the ‘final frontier’ in biomarker development.

Metabolomics is the agnostic study of all the low molecular weight compounds in a biological sample to provide a dynamic down-stream measure of a whole system’s activity defined as the metabolome; a global measure analogous to the genome. The metabolome reflects the genome, epigenome, transcriptome and proteome. It also reflects current exposure experience such as diet.

Crucially to public health, the metabolome has been shown to be reflective of disease state. As such, it represents a rich resource for the identification of exposure, predictive, diagnostic and prognostic biomarkers. With the advancement of high-throughput technologies, metabolomics is now emerging as a powerful and unique tool that will make a substantial impact on discovery-driven science.

In this nanocourse, we will provide an overview of metabolomics, the concepts and technologies underlying it, and recent developments in the field. We will provide the basic framework for planning and executing successful metabolomic studies, enabling nanocourse participants to take advantage of this exciting new technology in their future work.

Schedule: 

First Session (open to all without prior registration): Wednesday, June 10th 1:30-4:30 PM
Location: FXB G12 (Harvard Chan School of Public Health)

Second Session (limited to registered students): Wednesday, June 17th 1:30-4:30 PM
Location: FXB G3 (Harvard Chan School of Public Health)

 

DROP DEADLINE: Wednesday, June 3, 2015

 

 AUDITORS (Post-Docs, Faculty, or Staff) DO NOT NEED TO SIGN UP TO ATTEND THE 1st SESSION.  PLEASE DO NOT ENROLL