CB 399: Hallmarks of Cancer Biology - Reading Course Summer 2012

Hallmarks of Cancer Biology - Reading Course
Nanocourse Lecturers:
Curriculum Fellow: Narveen Jandu, PhD, narveen_jandu@hms.harvard.edu

Note: Only students who have received permission to take this course can sign-up.

Also, if you aren't taking this course for credit, you still need to sign-up.

This course is for students actively pursuing cancer biology research.  Each day of the course will cover a major relevant topic in Cancer Biology Research. These topics will be explored in-depth using recent papers high profile. Topics to be covered include:  Cancer Cell Signaling,  Metastasis and EMT, Cancer Genomics, Cancer and microRNAs and Cancer Stem Cells.  Discussions will focus on the chosen paper, why it is considered a seminal paper in Cancer biology Research and the impacts of the paper on future research, prevention and treatment.  Students are required to read and come prepared to discuss the assigned papers.

Time: 4:00pm – 5:30pm

Location: Smith 964

Schedule:

Week 1
Day 1: Mond, Aug 20th - p53 -tumor suppressor genes and cancer
Dr. Pablo Hollstein from Dr. Cichowski's Lab - p53 papers

Day 2: Tues, Aug 21th - GENOME INESTABILITY AND CANCER
Dr. Esther Baena from Dr. Orkin´s Lab - Genomic and Cancer paper

Day 3: Wed, Aug 22th - SIGNALING NETWORK IN CANCER
Dr. Pablo Hollstein from Dr. Cichowski's Lab - Signaling papers

Day 4: Thurs, Aug 23th - microRNAs and CANCER
Dr. John Powers from Dr. Daley´s Lab - miRNA and Cancer paper

Week 2
Day 5: Mond, Aug 27th - METASTASIS, EMT & CANCER
Dr. Christin Chaffer from Dr. R. A. Weinberg´s Lab - EMT and Metastasis paper

Day 6: Tues, Aug 28th - CANCER STEM CELLS AND CANCER
Dr. Christine Fillmore from Dr. Kim´s Lab - CSCs paper

Day 7: Wed, Aug 29th - TUMOR MICROENVIRONMENT
Dr. Zafira Castaño from Dr. McAllister´s Lab - TME and Metastasis paper

Day 8: Friday, August 24, 2012 - Course Wrap-up

 

Assignment: Please prepare at least one written in-depth and detailed question on the paper to be discussed or the topic to be discussed each day. This question can be, should be thoughtful and aimed at stimulating an insightful discussion. You may choose to prepare very direct questions, open-ended questions or questions around unresolved issues within the field and literature.