CB 399: Kinases and Kinase Inhibitors in Cancer Fall 2009

Intellectual Unit: Understanding the Complexity of Cancer

Kinases and Kinase Inhibitors in Cancer

Course Director: Tom Roberts

Course Lecturers: Nathanael Gray, Tom Roberts and Jean Zhao

Curriculum Fellow: Dr. Susan Koegel

Kinases play critical roles in promoting intracellular signaling cascades responsible for essential cellular processes, including proliferation, growth, apoptosis, and motility. Thus, inappropriate activation of kinases can lead to tumorigenesis. This connection makes kinases both attractive and effective drug targets for treating malignancies. In this course, we will explore the role of kinases in cancer and focus on the current development, success, and challenges of small-molecule kinase inhibitors.

First Meeting: Tuesday, October 13th from 1:15-4:45 pm

Location: TMEC Blgd., Room 250

Second Meeting: Friday, October 16th from 2-4:30 pm

Location: TMEC Bldg., Room 448

Recommended Readings

Instructions and Course Documents