CB 399: Approaches and Methods for the Study of the Aging Human Brain and Body Fall 2010

Intellectual Unit:

Approaches and Methods for the Study of the Aging Human Brain and Body
Nanocourse Director: Philip De Jager
Curriculum Fellow: Catherine Dubreuil (Catherine_Dubreuil@hms.harvard.edu)
Lecturers: Dr. David Bennett, Dr. Denis Evans, Dr. Brad Dickerson and Dr. Lori Chibnik

The study of our aging population is a national priority given demographic trends. Here, we present an introduction to the challenges and solutions that have emerged in the study of aging in humans, with a focus on the function of the brain and the clinical expression of neurodegenerative processes into clinical syndromes such as Alzheimer’s disease and Parkinson’s disease. Students will be presented with important concepts regarding the definition and measurement of aging-related traits. Further, different specialists will present different study strategies with a particular attention to the use of longitudinal data. The analysis of multiple different modalities of data will be discussed. At the conclusion of the course, students should have a general understanding of the heterogeneity of aging individuals, the overlap among clinical conditions resulting in dementia and functional impairment as well as different approaches to their study.

 

Schedule: 

First Session: Tuesday, October 19, 8:30 - 12:30 pm
Location: TMEC Building, Rm. 227
 
Second Session: Wednesday, October 27, 2 – 5 pm

Location: TMEC Building, Rm. 447
 

Drop Deadline: Tuesday, October 12, 2010

 

Day 2 – Student discussions

We will review the concepts presented on day 1 and quickly move on to student presentations that will be based on a series of topics targeting the integration of clinical and imaging data with genome-wide genetic variation data, blood and cerebrospinal fluid biomarker data to evaluate successful and less successful strategies in the study of aging and neurodegeneration.

  

 

 

AUDITORS (Post-Docs, Faculty, or Staff) DO NOT NEED TO SIGN UP TO ATTEND THE 1st SESSION.  PLEASE DO NOT ENROLL.