CB 399: How to Build a Blood Vessel Fall 2010

Intellectual Unit:

How to Build a Blood Vessel
Nanocourse Director: Joyce Bischoff
Nanocourse Lecturers: Rakesh Jain, Joyce Bischoff and Joanne Chan
Curriculum Fellow: Latishya Steele

This nanocourse will focus on the cellular events and signaling pathways used in making blood vessels during development, in pathological states such as tumor angiogenesis and bio-engineering of blood vessels for regenerative medicine. We will begin with how embryonic blood vessels are formed using zebrafish, mice and culture cells as model systems. The role of vascular progenitor cells in vessel development and the potential of these cells for bioengineering vessels for regenerative medicine will be examined. Finally, we will discuss how dysregulation of signaling pathways contributes to formation of vessels in pathological conditions.  As blood vessels line all organs and tissues, defects in their formation underlie human diseases including cancer, diabetes and macular degeneration.

PLEASE CLICK HERE FOR INFORMATION REGARDING READINGS FOR THE COURSE AND HERE FOR THE SECOND SESSION ASSIGNMENT.

 
First Session: Thursday, January 20, 2011 2 – 5 pm
Location: TMEC Building, Rm. 209
 
Second Session: Thursday, January 27, 2011 2 – 5 pm
Location: Karp 12th Floor Conference Room

DROP DEADLINE: Thursday, January 13, 2010

 

Pre-reading for first session (please scroll down for links to annotation for pre-reading and .pdfs of papers below) 

Assignment for second session:

In the second session, participants will read primary literature exploring themes addressed in the first session.  Participants will form teams of 3-4.  Each team will read one of the papers listed and prepare a 5-slide presentation that will highlight the key findings and significance of that paper and include strengths and weaknesses found within. The presentations will be given during the second session; we anticipate 30 minutes of presentation and discussion/paper.  The links to the papers that can be used for these presentations are posted to this website below. Please refer to the Word document for an annotation of the papers.   Please view your group assignments below; these will be determined at the end of the first session.  Please read the papers assigned to groups that are not your own to be prepared to contribute to the discussion.

PLEASE LOG IN BELOW TO ACCESS THE "INFORMATION REGARDING PAPERS FOR SECOND SESSION ASSIGNMENT" DOCUMENT BELOW FOR ADDITIONAL INFORMATION.